Product Description, Technical Parameters, and Configuration

Instrument Introduction

The launch of LC 310 high-performance liquid chromatography is the crystallization of more than ten years of liquid chromatography research and development experience of Youli Company, which means that Youli Company has reached another new height in the research and development of liquid chromatography. This marks that Youli Company has achieved the best balance between high performance, high reliability, and ease of use in liquid chromatography research, providing professional users with high-performance liquid chromatography.

The LC 310 high-performance liquid chromatograph has improved the separation, sensitivity, speed, accuracy, and reliability of HPLC; The advanced parallel pump head and one-way valve design concept enables users to ensure the accuracy, pulsation and other performance indicators of infusion under various usage conditions, with a small system dead volume and a 100% improvement in working capacity.

Performance characteristics

Multiple configurations for free selection

When designing the LC 310 high-performance liquid chromatograph, the market demand for liquid phase applications was fully considered, and corresponding hardware configurations were optimized according to the actual situation of different customers, providing customers with more choices.

The LC 310 high-performance liquid chromatograph mainly includes two configurations, namely: isocratic liquid chromatograph and binary high-pressure gradient liquid chromatograph.

More in line with the needs of your laboratory

Analyze the market and be considerate of users. Approaching the LC 310 liquid chromatograph, you will be pleasantly surprised to discover all the care and convenience it brings you. Just as you have always dreamed of, the experimental analysis results may be easier than you expected. Moreover, due to your busy work schedule, you are unable to consider the complex functions that the laboratory cannot use. Therefore, you will be pleased to find that the LC 310 system does not have any unnecessary features for your laboratory that you do not need.

Excellent peripheral performance

The full utilization of the superior performance of the product cannot be achieved without the reliability of the system hardware configuration. In the design and manufacturing of the LC 310 new durable liquid chromatography system components, Yuli first considers the reliability of hardware configuration, the lifespan of each component, and the quality during assembly. For each module, the new predictive function can identify and inform users in a timely manner before problems occur, making HPLC more reliable and eliminating problems in a timely manner.

LC-310 High Pressure Infusion Pump

The microprocessor controlled reciprocating double plunger parallel pump has the characteristics of high working pressure resistance, small pulsation, stability and reliability, and easy operation. Due to the alternating infusion of the dual pump heads, the life of the piston rod and sealing ring is twice as long as that of the conventional series pump under the same infusion volume.

The mechanical components of the pump are all designed with computer-aided design. Therefore, the extraordinary machining accuracy and strict pressure testing of each pump ensure that there is no leakage of the pump, allowing you to use it with confidence.

It has a status monitoring function. The microprocessor controls the flow rate of the pump in real time and detects the infusion pressure. In the event of pressure exceeding the limit, an alarm will sound and the pump will automatically stop running.

Design of one-way valve

The valve core body, gemstone ball seat, and gemstone ball form a unified structure, which has the advantages of simple structure and good sealing performance, and improves the performance of high-pressure infusion pumps

The flow accuracy reduces flow pulsation and has the characteristics of easy installation and replacement. Floating guiding design: Adopting a floating plug mechanism, the service life of the plug rod and sealing ring is extended, and stable infusion can be carried out for a long time.

LC-UV310 UV Visible Light Detector

Digital data processing and control to reduce baseline noise and drift to a new limit. The detector directly outputs digital signals to the LC 310 workstation, avoiding signal distortion and interference caused by multiple analog-to-digital conversion of chromatographic signals in general UV detectors. The excellent flow pool design has made breakthroughs in improving various performance indicators of the instrument. The optical path system adopts a precise positioning structure with high accuracy and small deviation. The deuterium lamp and optical path system adopt thermal isolation technology, which shortens the stabilization time and reduces the impact of deuterium lamp heating on the optical path system to * *. The preamplifier adopts a high impedance, low drift instrument amplifier and a high-resolution A/D converter. Under conventional analysis, the dynamic range can reach 104, ensuring the accuracy of logarithmic operations. Due to the use of digital output function, the detector can be directly connected to a computer through an RS232 serial port without the need for any data acquisition unit. High quality precision machining and patented technology, flow cell - the heart of the UV detector. The flow cell adopts a tapered hole design, which improves the signal-to-noise ratio by 23.8% compared to the traditional straight hole design, greatly enhancing the sensitivity of the detector.

High pressure mixer design

The high-pressure mixer adopts a mixing design concept of narrow and flat pipelines, which can increase the mixing surface area of two-phase liquids when they come into contact, thereby achieving a * * * mixing effect; At the same time, the mixer also has the characteristics of small volume and high mixing efficiency, which can make the liquid mix evenly in a short time, greatly reducing the delay time.

Easy analysis originates from:

Digital computer intelligent fully controlled liquid chromatography instrument.

Reciprocating double plunger parallel pump. More stable and reliable, with a longer service life.

The appearance is novel, the operation is convenient, and it reflects humanization.

Excellent performance indicators, comparable to popular foreign models.

The optical system adopts precision positioning structure and thermal isolation installation technology, which has high accuracy,

The characteristics of small offset and short stability time.

**All components are processed using advanced CNC technology.

The chromatographic data processing system software has powerful functions and is easy to learn

The supporting LC-310 chromatographic data processing system workstation software realizes the fully automatic integration of detector, high-pressure infusion pump, column temperature box and other chromatographic unit components. It has powerful instrument centralized control, status feedback, spectral data processing, report output functions and simple and fast operation methods, which can easily realize the development of various conventional sample analysis and application methods. The software adopts a fully CNC system, and the digital operation makes the process simpler and has extremely high accuracy.

The software mainly consists of three modules, namely LC-310 liquid chromatography control module, chromatography data processing module, and report output module.

Simple and clear real-time control interface

The real-time control interface includes basic settings for all UV detectors and high-pressure infusion pumps, which can be directly inputted by clicking buttons with the mouse and using the keyboard. Users can control the deuterium lamp switch, real-time sampling data conversion, adjust filtering time and wavelength settings as needed, and also set corresponding events and enable spectral scanning programs during operation. Users can also control the switch of the pump at any time and adjust its pressure upper and lower limits and real-time flow accordingly. In addition, during gradient elution, users can directly complete it through the time program window on the interface and monitor the real-time flow rate of the entire elution process.

Convenient and clear parameter settings

In the parameter setting dialog box, users only need to directly input different parameter values as needed to determine peak processing parameters and system settings parameters.

Technical indicators

Basic technical specifications of LC-P310 high-pressure constant flow pump:

Flow range: 0.001-9.999mL/min (adjust flow rate in 0.001mL/min steps)

Flow stability error: Sr ≤± 0.3% RSD<>

Flow setting error: Ss ≤± 0.5% (1mL/min water, 5-10Mpa room temperature)

Pressure linearity and accuracy: Display pressure error ≤± 0.5Mpa (0-42MPa)

Pressure pulsation: ≤ 0.1 MPa (flow rate 1mL/min, pressure 5-10Mpa)

Sealing pressure of the pump: 42MPa, duration of 10 minutes, pressure drop<>

**High working pressure: 42MPa (0.001-9.999mL/min)

Dimensions: 450mm x 300mm x 160mm (length x width x height)

Basic technical specifications of LC-UV310 UV detector:

Wavelength range: 190-680nm

Spectral bandwidth: 8nm

Wavelength indication error: ≤ ±1nm

Wavelength repeatability better than 0.1um

Baseline noise: ≤ 2 × 10-5AU (dynamic)

Baseline drift: ≤ 2 × 10-4AU (dynamic)

**Small inspection measurement: 1 × 10-8g/mL (methanol solution of naphthalene)

Dimensions: 450mm x 300mm x 160mm (length x width x height)

Standard configuration

LC310 standard equipotential configuration

LC-P310 high-pressure constant current pump: 1 unit

LC-UV 310 UV detector: 1 unit

LC-CO310 chromatography column temperature chamber: 1 unit

7725i manual injection valve: 1 set

LC-WS310 Chromatography Management Workstation: 1 unit

Liquid chromatography column: 1

LC310 standard gradient configuration

LC-P310 high-pressure constant current pump: 2 units

High pressure mixer: 1 set

LC-UV 310 UV detector: 1 unit

LC-CO310 chromatography column temperature chamber: 1 unit

7725i manual injection valve: 1 set

LC-WS310 Chromatography Management Workstation: 1 unit

Liquid chromatography column: 1

Optional configuration

Liquid phase flat head micro injection needle

Solvent filter (with pump)

Brand computer

Brand printer

regulated power supply

application area

The intelligent fully controlled liquid chromatography LC310 is suitable for analyzing organic compounds with high boiling points, low volatility, unstable under heat, high molecular weight, and different polarities; Bioactive substances and various natural products; Synthetic and natural polymer compounds, etc. In nature, 80% of organic matter can be analyzed and detected using liquid chromatography systems. This system is mainly applied in fields such as food safety, drug analysis, environmental protection, health and epidemic prevention, agriculture, forestry, fisheries, animal husbandry, manufacturing, petrochemicals, quality supervision, teaching and research, and water conservancy systems.